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Aminomethylphosphonic acid : ウィキペディア英語版
Aminomethylphosphonic acid

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Aminomethylphosphonic acid (AMPA) is a weak organic acid with a phosphonic acid group. It is one of the primary degradation products of the herbicide glyphosate.〔(Environmental Fate of Glyphosate ), Jeff Schuette, Department of Pesticide Regulation, California〕
AMPA has low toxicity which is comparable to that of glyphosate and it is therefore considered to be of no greater toxicological concern than glyphosate itself.〔(Pesticide Residues in Food - 1997 ), FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group〕 AMPA has been shown to be broken down further by manganese oxide which occurs naturally in soil,〔K. A. Barrett and M. B. McBride. Oxidative Degradation of Glyphosate and Aminomethylphosphonate by Manganese Oxide. Environ. Sci. Technol., 2005, 39 (23), pp 9223–9228〕 or to phosphoric acid via bacterial action 〔Pipke R, Amrhein N. (1988) Isolation and characterization of a mutant of Arthrobacter sp. strain GLP-1 which utilizes the herbicide glyphosate as its sole source of phosphorus and nitrogen. Applied and Environmental Microbiology 54(11): 2868-2870.〕〔Forlani G, Mangiagalli A, Nielsen E, Suardi CM. (1999) Degradation of the phosphonate herbicide glyphosate in soil: Evidence for a possible involvement of unculturable microorganisms. Soil Biology and Biochemistry 31: 991-997〕 and ultimately to carbon dioxide and inorganic phosphate.〔Backgrounder: Glyphosate does not degrade to phosphorous acid in the environment. Monsanto. 2005〕
==References==


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